(19) demonstrated that the density of tumor-infiltrating CD3 and CD8 T cells could predict the recurrence of HCC in patients who underwent a hepatectomy (CD3, odds ratios (OR) = 5.8; CD8, OR= 3.9), and was independent of other predictive clinicopathological factors, such as vascular invasion and HCC cell differentiation. Here, CD8A is linked to hepatocellular carcinoma.