This model is a simple and easy-to-use calculator, integrating tumor characteristics of HCC patients: tumor size, number, portal vein tumor thrombus, AFP, liver function, albumin, total bilirubin, γ-GGT, LDH, inflammatory index, white blood cell counts, antiviral therapy, and immune index—T cell counts and CD8 T cell counts. This evidence concerns the gene AFP and hepatocellular carcinoma.