Moreover, we used single-cell sequencing data to further explore the expression of ATR in designated cell types of lung adenocarcinoma and found the expression of ATR in stromal cells (Fibroblasts, Epithelial cells, Endothelial cells) of tumor patients is at a lower level when compared with normal patients, but the expression of ATR in the immune cells (Myeloid cells, B lymphocytes, MAST cells) of tumor patients is at a high level, except for T/NK cells (Figure 5). This evidence concerns the gene ATR and lung adenocarcinoma.