CDKN2A and acute lymphoblastic leukemia: CDKN2A/B is one of the most frequent abnormal genes in ALL and can be detected by fluorescence in situ hybridization (FISH), multiplex ligation-dependent probe amplification (MLPA), array-based comparative genomic hybridization (aCGH) analysis, and single-nucleotide polymorphism array (SNPA) (2–6).