reported that pediatric ALL with CDKN2A/B deletions had recurrent cytogenetic abnormalities including high frequencies of TCF/PBX1, BCR/ABL, hyperdiploidy, and KMT2A, and low frequencies of ETV6/RUNX1 compared to patients without CDKN2A/B deletions (5, 11). This evidence concerns the gene HNF4A and acute lymphoblastic leukemia.