However, we also found that there was no significant difference of DP and CD4lowCD8high T cells expressing CCR5 between the disease groups (TB,HIV, and HT group), suggesting coexistence with HIV or coexistence with TB may not influence CCR5 expression on circulating DP and CD4lowCD8high T cells in comparison to TB or HIV mono-infection. The gene discussed is CCR5; the disease is infection.