The mesenchymal‐like phenotype of cancer cells is associated with tumor growth, invasion, metastasis, and resistance to treatment.[60] The loss of E‐cadherin in cancer cells impairs the balance between cell‐cell adhesions and integrins‐mediated cell‐ECM adhesion, resulting in the occurrence of invasion and initiating spreading to distant organs.[61] Upon arrival, mesenchymal‐like cells revert to showing epithelial characteristics, thus restoring their ability to proliferate and undergo epithelial growth at remote organ sites. The gene discussed is CDH1; the disease is neoplasm.