CARD11 and diffuse large B-cell lymphoma: The emergence of high-throughput technologies such as whole exon sequencing and deep sequencing has found a variety of molecular mutations and single nucleotide polymorphisms including MYD88, EZH2, CARD11, FOX O 1, involving the abnormalities of multiple signaling pathways including BCR, NK-κB, NOTCH, Toll-like receptors and PI3K, which makes the more in-depth understanding of the pathogenesis and disease susceptibility of DLBCL.