We used 20 TFs for further analysis, 16 of which were significantly differentially expressed in depression samples compared with those in normal samples as shown in Figure 6A, and 11 TFs were significantly related to GTF2F2, based on their expression levels in the high and low GTF2F2 expression subgroups (as shown in Figure 6B). The gene discussed is GTF2F2; the disease is major depressive disorder.