BG-P400-TAT is a novel chemical entity that affects the transcription of a substantial panel of genes relevant to cancer cell proliferation, apoptosis, and cancer-linked angiogenesis mediated via its TAT binding to integrin αvβ3, a plasma membrane protein preferentially expressed by cancer cells while BG binds to the norepinephrine transporter expressed in neuroblastoma and neuroendocrine cancers. The gene discussed is TAT; the disease is cancer.