IL1B and non-small cell lung carcinoma: As detected by ELISA and RT-qPCR, compared with normal lung epithelial cell line 16HEB, the expression of IL-1β and lncRNA CHRF was higher in the three NSCLC cell lines H460, H1299, and A549, of which the H460 cell line with the highest expression of IL-1β and lncRNA CHRF was selected for subsequent experiments (Figure 1D, E).