LPCAT3 and atherosclerosis: However, recent studies have found that bone marrow cell-specific LPCAT3 deficiency does not significantly change atherogenesis 35, whereas hematopoietic cell-specific LPCAT3 deficiency promotes atherosclerosis, and the transplantation of hematopoietic cells from constitutive LPCAT3-deficient mice in LDLR-/- mice leads to increased atherosclerotic lesions 52.