On comparison of FUZ expression levels among the normal control cells (HBE) and different NSCLC cells using western blot analysis, the results showed that FUZ was highly expressed in NSCLC cells, and we ultimately selected A549 and H1299 cells to determine the effects of FUZ knockdown and overexpression (Figure 1B). This evidence concerns the gene FUZ and non-small cell lung carcinoma.