RNF213 and multiminicore myopathy: In addition, numerous genome-wide associated studies revealed that the ring finger protein 213 (RNF213) p.R4810K mutation was an important susceptibility gene for MMD through whole blood samples (Kamada et al., 2011; Liu et al., 2011; Miyawaki et al., 2012; Duan et al., 2018; Cheng et al., 2019).