However, compared to wild-type controls, both male and female mutant mice had fewer marbles buried (male: F1, 28 = 8.52, p = 0.0069, female: F1, 24 = 3.88, p = 0.04; Figures 4F–H), suggesting Kdm6b haploinsufficiency causes lower levels of anxiety-like behaviors in home cages. Here, KDM6B is linked to Anxiety.