MAP2K7 and breast carcinoma: Next, to further clarify the role of the MAPK-ERK pathway to CBP recruitment in the ASC-induced proliferation of breast cancer cells, we incubated the MDA-MB-231 cells with a MEK inhibitor, a JNK inhibitor, and an anti-SCF antibody and analyzed the changes in p-ERK and CBP expression levels using western blot.