It has been reported that CBP, as a transcriptional coactivator, could coordinate with RFPL-3 and regulate the hTERT transcriptional activation in lung cancer [16], and our results shown higher expression levels of RFPL-3 and hTERT in the indirect coculture of MDA-MB-231 cells with ASCs (Figure 3(a)) and shown that RFPL-3 was localized in the nuclei of MDA-MB-231 cells, with CBP (Figure 3(b)). This evidence concerns the gene RFPL3 and lung cancer.