TYK2 and neoplasm: Taken N stage as an example, the expression of TYK2 in HNSC tumor subgroups with N2 stage was significantly higher than that with N0 stage (p.adj = 0.006); and the expression of TYK2 in HNSC tumor subgroups with N2 stage was significantly higher than that with N1 stage (p.adj < 0.001), while there was no significant difference for the other comparisons (p > 0.05).