IL6 and cancer: - Cytokine storm- IL-6 enhancement: directly correlated with the prognosis of patients with COVID-19 and also a driver of tumorigenesis and anti-apoptosis signaling, which is a key biomarker of cancer risk, diagnosis, and prognosis- Exhaustion of T lymphocytes contributes to weakened T cell activity- ICI and CAR-T cell therapies may exacerbate the COVID-19 hyperinflammatory state and increase mortality in cancer patients