CXCL8 and pancreatic neoplasm: Moreover, pancreatic cancer cells can recruit TANs by secreting chemokines of the CXC family, specifically CXCL6 and CXCL8 or CXCL1–3 and CXCL5–8 that are recognized by CXCR1 or CXCR2 receptors expressed on neutrophils (90).