A nomogram was developed for the composite outcome based on C3 deposits and RPS class (Figure 4), which provides a more intuitive assessment of survival for individual DN patients—for example, a class III DN patient with no C3 deposits would have a total score of 66.4, which corresponds to 15 and 50% probabilities of adverse kidney outcome within 1 and 3 years, respectively. The gene discussed is C3; the disease is liver dysplastic nodule.