HIF1A and colitis: So we conducted an alternative experiment of DSS-induced colitis treated with DMOG, which is a cell permeable and competitive inhibitor of HIF-PH, and thus results in HIF-1α stabilization and accmulation in vitro and in vivo (Milkiewicz et al., 2004; Cummins et al., 2008; Heinis et al., 2010).