Moreover, the IFN-γ response to the ancestral peptide pool was similar to that observed in response to the Delta peptide pool in both patients with MS (ancestral: median 5.11 pg/ml, IQR: 0.87–19.9 pg/ml; Delta: median 6.1 pg/ml; IQR: 0.82–14.9) and in “no MS” subjects (ancestral: median 3.89 pg/ml, IQR: 1–79 pg/ml; Delta: median 4.56 pg/ml; IQR: 0.16–95.2; Figure 1A). This evidence concerns the gene IFNG and myeloid sarcoma.