Among the children with sepsis, the stress state not only increased protein decomposition, but also increased the release of inflammatory cytokines, vascular endothelial cell damage, microcirculation disorders, aggravated capillary leakage, liver dysfunction, and liver protein synthesis ability decline, which resulted in a reduction in the total serum protein, especially albumin (30, 31). The gene discussed is ALB; the disease is Decreased liver function.