We previously showed that alternative splicing of VEGFA isoforms is modulated, in breast cancer (BC) cells carrying a mutated TP53 gene, by a ribonucleoprotein (RNP) complex enclosing long non-coding RNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), splicing factor SRSF1 (Serine And Arginine Rich Splicing Factor 1), ID4 (inhibitor of DNA-binding 4) protein and mutant p53 protein12,13. The gene discussed is VEGFA; the disease is breast cancer.