T-ALL displayed higher EHMT2/G9a expression compared to other tumor types [16] (Fig. 1D), normal human thymocytes (Fig. 1E, Supplementary Fig. 1G), or lymphocytes (Fig. 1F) independent from the activation of known transcription factor or recurrent mutations (Supplementary Fig. 1H). This evidence concerns the gene EHMT2 and acute lymphoblastic leukemia.