In addition to SNPs known to be related to diseases such as hemochromatosis, atransferrinemia or iron deficiency anemia19,34–38, and variants that had previously been reported for at least one of the iron traits21,39, we identified 11 protein-altering variants in novel iron status loci (Supplementary Data 4): rs9427398 (FCGR2A), rs2437150 (SPRTN), rs1047891 (CPS1), rs41274050 (A1CF), rs1935 (JMJD1C), rs3742049 (COQ5), rs4149056 (SLCO1B1), rs2070863 (SERPINF2), rs883541 (WIPI1), rs1800961 (HNF4A) and rs738409 (PNPLA3). This evidence concerns the gene COQ5 and Congenital atransferrinemia.