HR and hypotrichosis: The most diverse breeds include three of the newer cat breeds: the short-legged Munchkin, produced from a sibling mating followed by regular non-pedigreed cat outcrosses [7,67]; the Highlander, a crossbreed of two recent experimental hybrid cat breeds the Desert Lynx and Jungle Curl; and the Lykoi breed founded by unrelated cats expressing hypotrichosis, whose unique sparse and roaned coat phenotype may be caused by any of six different variants of the HR gene from six independent lineages found in four different states of the United States, Canada and France [76].