S100A6 and proximal spinal muscular atrophy: For example, in the Highlander, one of the most genetically diverse breeds, we found the presence of disease-associated variants for HCM (discovered in the Ragdoll), PK-def, rdAC-PRA, PRA (discovered in the Bengal) and Spinal Muscular Atrophy (discovered in the Maine Coon) which represent targets for genetic screening and management in the breed.