Osteochondrodysplasia and Earfold is a highly penetrant autosomal dominant condition caused by a missense variant (c.1024G>T) in the TRPV4 gene resulting in congenital degenerative osteochondrodysplasia or “Scottish Fold Syndrome”, manifesting as skeletal deformities such as a short, thick, inflexible tail and malformation of the distal fore- and hindlimbs, which can lead to a stilted gait [46]. This evidence concerns the gene TRPV4 and osteochondrodysplasia.