MERTK and EGFR interaction was dramatically reduced in OSIR cells (Figure 3, I and J), and downstream signaling (Figure 3B), cell expansion (Figure 3C), and colony formation (Figure 3D) were more affected by MRX-2843 compared with parental cells, highlighting the potential benefit of inhibiting MERTK kinase activity in OSIR EGFRMT NSCLC. Here, EGFR is linked to non-small cell lung carcinoma.