DCTN1 and amyotrophic lateral sclerosis: Additional DCTN1 mutations lying both in DCTN1 CAP-Gly domain and in its dynein-binding domain have then been identified in ALS (Münch et al. 2004; Stockmann et al. 2013; Liu et al. 2014, 2017), including those forms with an FTD component (Münch et al. 2005).