For responsiveness to immunotherapy, the expression of programmed death-ligand 1 (PD-L1) on tumour cells was found to be predictive for immunotherapy efficacy (Herbst et al. 2016; Gandini et al. 2016; Xia et al. 2019; Fehrenbacher et al. 2016; Gandhi et al. 2018). This evidence concerns the gene CD274 and neoplasm.