These genetic polymorphisms are associated with different levels of MBL expression and activity.4, 5Various studies on the association ofMBL2genetic polymorphism and/or MBL plasma levels with severe infections, sepsis, and septic shock have shown an increased risk of developing sepsis in patients with MBL deficiency and a negative outcome.5, 6. Here, MBL2 is linked to hyperinsulinemic hypoglycemia, familial, 4.