MMP2 and tricho-dento-osseous syndrome: There are several syndromes where taurodontism has been identified like osteogenesis imperfecta, Torg–Winchester syndrome, TDO, cleft lip, and palate.73TDO syndrome is associated with DLX3 gene mutations, which are also associated with amelogenesis imperfecta hypoplastic hypomaturation with taurodontism.74Taurodontism is also seen in Torg–Winchester syndrome, which is associated with matrix metalloproteinase 2 (MMP2) genetic mutations.75