CD8A and psoriasis: HLA-C encodes an major histocompatibility complex (MHC) class I receptor involved in the immune system and is involved in the presentation of antigens to CD8+ T lymphocytes.7In recent years, many studies have been conducted to examine the contribution of the HLA-Cw6 allele to the pathogenesis of psoriasis.8The prevalence of HLA-Cw6 varies worldwide, ± 16% in Africa, 8.5 to 12% in Europe, and 3.5 to 7.8% in Asia.9In a study, psoriasis was also associated with HLA-C*12:03.10The HLA-C*12:02 allele was related with late-onset disease in Japanese patients.11