CD8A and congenital T-cell immunodeficiency: When mice were fed an obesogenic diet, in spite of a similar weight gain and insulin response in Slc16a1f/fTcellcre compared with Slc16a1f/f mice, thus excluding a major role for MCT1 T cell deficiency on systemic metabolism, a reduced number of CD8+ T cells was detected in the epiWAT of Slc16a1f/fTcellcre compared with Slc16a1f/f mice coupled to smaller adipocytes.