TNF and rheumatoid arthritis: Among them, Th17 cell differentiation (hsa04659), rheumatoid arthritis (hsa05323), NF-kappa B signaling pathway (hsa04064), TNF signaling pathway (hsa04668), Th1 and Th2 cell differentiation (hsa04658), and Toll-like receptor signaling pathway (hsa04620) have been reported to be closely related to RA.