VWF and coronary artery disorder: There is uncertainty in the literature on this association.2, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26We observed no significant association of its carrier protein, VWF, with CVD; a meta-analysis of the association of VWF level with CHD in 15 studies with 6,556 cases showed a significant association: HR per 1 SD, 1.16 (95% CI, 1.10–1.22).6Plasma VWF, as its carrier protein, is correlated with plasma factor VIII.17, 18