However, there was an additive interaction between anti-ENO1-P6 and anti-PDIA3 total IgGs on the development of miscarriage (RERI = 23.6, 95% CI = −18.1, 65.3; AP = 0.79, 95% CI = 0.47, 1.11; SI = 5.37, 95% CI = 1.03, 27.87). This evidence concerns the gene PDIA3 and spontaneous abortion.