Then, module analysis of the 113 key OGEs was performed using MCODE and the CytoNCA plugin to obtain 6 core genes (CXCL8, MAPK1, AKT1, SRC, VEGFA, and IL-6), which might play important roles in the effects of JQH against WD-associated liver fibrosis. Here, MAPK1 is linked to Hepatic fibrosis.