SFPQ and lung cancer: IHC analysis further demonstrated that there were a large number of human CD44v6 and SFPQ positive cells in the lung tissues of mice receiving the control NSC lung cancer-MSCs (Figures 5J, K), while there were no cells expressing human CD44v6 in the lung tissues of mice receiving SFPQ knockdown MSCs (Figures 5M, N), indicating SFPQ plays an important role in cancer metastasis and SFPQ knockdown could block metastasis.