EIF6 and cancer: In this respect, eIF6 can selectively bind to IFs in mammalian cells, although the biological function of such complexes is not yet been determined, there is some evidence that the complexes formed by eIF6 and IFs are highly regulated during the oogenesis of Xenopus, suggesting they are probably contributing to the early development of embryo, which cells possessed the common feature of continuous mitosis with cancer cells (43).