Specifically, in our panel of 10 AML lines only 3 showed detectable PKCε expression (Mv-4;11, U937 and OCI-AML5; Supplementary Figure 16) and none demonstrated overexpression, unsurprisingly while we achieved knockdown in U937 and Mv-4;11 (Supplementary Figure 17) we observed no significant impact on cell growth, viability or chemosensitivity (Supplementary Figures 18, 19). The gene discussed is PRKCE; the disease is acute myeloid leukemia.