The present study found that PDLIM1, PDLIM2, PDLIM3, PDLIM4, PDLIM6, and PDLIM7 mRNA levels were decreased but that the PDLIM5 mRNA level was increased in both unpaired and paired samples in TCGA-PRAD cohort. This evidence concerns the gene PDLIM5 and prostate adenocarcinoma.