The present study found that PDLIM1, PDLIM2, PDLIM3, PDLIM4, PDLIM6, and PDLIM7 mRNA levels were decreased but that the PDLIM5 mRNA level was increased in both unpaired and paired samples in TCGA-PRAD cohort. The gene discussed is PDLIM1; the disease is prostate adenocarcinoma.