<h4>Introduction</h4>In outpatients, the World Health Organization recommends that the urine Alere Determine-tuberculosis lipoarabinomannan (AlereLAM) should be used to support the diagnosis of tuberculosis (TB) in people living with HIV (PLHIV) with CD4 counts ≤ 100 cells/μL or with signs of being 'seriously ill'. The gene discussed is CD4; the disease is tuberculosis.