When the cohort (n = 271) was stratified by ethnicity (Hispanic versus non-Hispanic), patients of Hispanic ethnicity (n = 87) were more likely to be younger (12 versus 15 years; P < 0.001) and to have a higher ALT (98 versus 73 U/L; P = 0.040) despite the same degree of obesity as the non-Hispanic patients (body mass index z score 2.27 versus 2.43; P = 0.006). The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.