In a study from Nature, researchers used intercellular CRISPR screening to identify PRFs (TIMMDC1, PDCD10, RPL21, GTPBP3, KIF23, PIK3R5, FOXO1, NFIA, ARPC2, HMGB2, NDUFV1, FADD, PACS2, HMHA1, CMC1, ANAPC7, and MIB2) in cancer cells. Here, ARPC2 is linked to cancer.