In a study from Nature, researchers used intercellular CRISPR screening to identify PRFs (TIMMDC1, PDCD10, RPL21, GTPBP3, KIF23, PIK3R5, FOXO1, NFIA, ARPC2, HMGB2, NDUFV1, FADD, PACS2, HMHA1, CMC1, ANAPC7, and MIB2) in cancer cells. The gene discussed is RPL21; the disease is cancer.