KRT16 and cancer: To define the possible role of E6 and E7 in the loading and spreading of miRNAs by EVs, a TaqMan-based miRNA A array was used to analyze hundreds of miRNAs associated to cancer in EVs derived from K16 cells (EV_K16) versus EVs derived from E6/E7 silenced K16 (EV_K16 sil).