To better understand if DNAm changes of our DNMT3A knockout iPSC clones are related to aberrant DNAm patterns in AML patients with DNMT3A mutations, we utilized 134 DNAm datasets of AML patients from The Cancer Genome Atlas (TCGA) without mutation in DNMT3A (n = 101), with R882 mutations (n = 18), or with other DNMT3A mutations (n = 15). The gene discussed is DNMT3A; the disease is acute myeloid leukemia.