IL1RN and acute respiratory distress syndrome: eNAMPT was among a panel of six biomarkers shown to be highly predictive of 28-day mortality in ARDS [12] and included Interleukin-6 [IL-6], Interleukin-8 [IL-8], Interleukin-1 receptor antagonist [IL-1RA], macrophage migration inhibitory factor [MIF], and Angiopoietin-2 [Ang-2].