And the expression of CKMT1A in the tumor tissues of COAD (Colon adenocarcinoma) (P < 0.001), GBM (Glioblastoma multiforme) (P < 0.001), KIRC (Kidney renal clear cell carcinoma) (P < 0.001), THCA (Thyroid carcinoma) (P < 0.05) was significantly lower than the corresponding control tissues. The gene discussed is CKMT1A; the disease is thyroid gland carcinoma.