Furthermore, the PrognoScan survival analysis demonstrated that the high and low expression of KCTD2 (HR = 0.13, Cox P = 0.010), KCTD5 (HR = 4.71, Cox P = 0.004), KCTD9 (HR = 0.50, Cox P = 0.032), KCTD12 (HR = 0.55, Cox P = 0.013) and KCTD16 (HR = 0.56, Cox P < 0.001) were significantly correlated with the OS of lung cancer patients (Fig. 4B). Here, KCTD9 is linked to lung cancer.