Pathway-specific analyses within each sarcoma subtype for which ≥20 samples were available (Fig. 4A, genes in each pathway listed in Supplementary Data 3) revealed that a number of pathways important in carcinomas were infrequently altered in sarcoma, including TGFβ, WNT, Hippo, Notch, and NRF2 (Fig. 4A, right panel). Here, TGFB1 is linked to carcinoma.