EGFR and inborn error of immunity: Genes involved in cell adhesion, antigen processing and presentation, chemokine signaling, Fc-gamma receptor-mediated phagocytosis and MAPK signaling and genes involved in primary immunodeficiency, Jak-Stat signaling, and Erbb signaling pathways were overrepresented in the clusters that showed higher expression in pDCs and lo-hi cells (Supplementary Fig. 2 and Supplementary Data 1).